Vaccines for Brazil
The checker above is preset on Brazil: list the cities or the next country of the trip, and it returns the CDC list, the yellow fever line and the price of each shot.
Travel vaccines CDC lists for most or some travelers on this trip
4 vaccines
plus 3 to discuss and routine vaccines up to date
| Yellow fever | CDC recommends the vaccine (Brazil) |
| Malaria | Prescription tablets for areas of Brazil |
| Longest lead time | 28 days before departure (Hepatitis B, 2 doses (Heplisav-B)) |
| Published price, these vaccines | $685 median, $638 to $930 |
Levels from the CDC destination pages; age 35 used for the Japanese encephalitis schedule. A list to take to a doctor, nurse or pharmacist, not medical advice.
| Disease | CDC level | Where | Start at least | Median price per dose |
|---|---|---|---|---|
| Yellow fever | CDC recommends the vaccine | Brazil | 10 days before | $269 |
| Hepatitis A | CDC: most travelers | Brazil | Any time before | $109 |
| Hepatitis B | CDC: most travelers | Brazil | 28 days before | $149 |
| Measles | CDC: most travelers | Brazil | Ask | $115 |
| Chikungunya | CDC: may be considered | Brazil | Any time before | $326 |
| Rabies | CDC: may be considered | Brazil | 7 days before | $419 |
| Typhoid | CDC: may be considered | Brazil | 14 days before | $174 |
Compiled by Radif Partners · Method and sources · CDC page reviewed September 3, 2026, read October 24, 2026
For Brazil, CDC lists hepatitis A and, for unvaccinated travelers younger than 60, hepatitis B for most travelers; typhoid is a vaccine to consider for rural areas, stays of a month or more and visits to family. Yellow fever vaccine is recommended for travelers aged 9 months or older going to most of the country: the states of the Amazon, the center west and the south, Distrito Federal with Brasília, Rio de Janeiro and São Paulo with their cities and coastal islands, designated areas of Bahia, and Iguaçu Falls. It is not recommended for travel limited to the areas not listed, Fortaleza and Recife among them. Brazil asks no certificate at entry, but some next borders do: the Dominican Republic for travelers coming from four Brazilian states, Costa Rica from anywhere in Brazil. Malaria tablets are advised for the Amazon states, not for Rio, São Paulo, Brasília or Iguaçu Falls. The median US county price is $269 for yellow fever and $109 a dose for hepatitis A.
A recommendation that reaches the big cities
Where CDC limits its yellow fever advice to parts of a country, the capital is often left out: Nairobi in Kenya, Lima in Peru, Bogotá in Colombia. Brazil's list goes the other way and names its largest cities. The vaccine is recommended for travelers 9 months or older going to the states of Acre, Amapá, Amazonas, Distrito Federal (including Brasília), Espírito Santo, Goiás, Maranhão, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Pará, Paraná, Piauí, Rio de Janeiro (including the city and all coastal islands), Rio Grande do Sul, Rondônia, Roraima, Santa Catarina, São Paulo (including the city and all coastal islands), Tocantins and designated areas of Bahia. Iguaçu Falls is named separately.
That leaves a short list of exceptions. CDC says the vaccine is not recommended for travel limited to any area outside that list, and gives the cities of Fortaleza and Recife as examples. In practice, the northeast coast (Ceará, Pernambuco, Rio Grande do Norte, Paraíba, Alagoas, Sergipe) is where a trip can fall outside the recommendation, while Bahia depends on where in the state the traveler goes, since only designated areas are included. A carnival week in Rio, a business trip to São Paulo or a visit to the falls from the Brazilian side all sit inside it. One dose is given at least 10 days before the trip, at $226 to $360 on the US county lists; with both hepatitis A doses and the visit fees, the pair comes to $516 at the median.
Yellow fever and hepatitis A for Brazil
Self-pay cost of these travel vaccines
$516
| Hepatitis A, 2 doses | $217 |
| Yellow fever, 1 dose | $269 |
No certificate at entry, but Brazil follows you
Brazil does not ask arriving travelers for a yellow fever certificate. The certificate question comes after Brazil. Because Brazil is a country with yellow fever risk, several destinations check travelers coming from it. The Dominican Republic requires a certificate from travelers 1 year or older arriving from four Brazilian states, Espírito Santo, Minas Gerais, Rio de Janeiro and São Paulo, including airport transits or layovers of more than 12 hours there. Costa Rica asks it from travelers 9 months or older arriving from Brazil, regardless of where in the country they stayed. The checker below follows a Brazil trip with a stop in Costa Rica; change the second country to test another route.
Brazil, then the next country
Travel vaccines CDC lists for most or some travelers on this trip
5 vaccines
| Yellow fever | CDC recommends the vaccine (Brazil) and Certificate required at the border (Costa Rica) |
| Malaria | Prescription tablets for areas of Brazil and Costa Rica |
| Longest lead time | 28 days before departure (Hepatitis B, 2 doses (Heplisav-B)) |
| Published price, these vaccines | $1,086 median, $920 to $1,330 |
Malaria in the Amazon, not on the coast
Malaria in Brazil is concentrated in the north. CDC lists transmission in all areas of Acre, Amapá, Amazonas, Rondônia and Roraima, which include Manaus and the river lodges around it. Maranhão, Mato Grosso and Pará have transmission too, with rare cases in their capitals, São Luís, Cuiabá and Belém. In Espírito Santo, Goiás, Minas Gerais, Mato Grosso do Sul, Piauí, Rio de Janeiro, São Paulo and Tocantins, CDC reports only rare cases and sporadic foci in rural and forested areas, with bite precautions instead of medicine. It states plainly that there is no malaria transmission in Brasília, Rio de Janeiro, São Paulo or at Iguaçu Falls.
P. vivax causes about 90% of infections and P. falciparum the rest; chloroquine resistance is reported, so the drugs CDC lists are atovaquone-proguanil, doxycycline, mefloquine and tafenoquine. A week on an Amazon river cruise means 16 atovaquone-proguanil tablets (about $23 at the price pharmacies pay), 37 doxycycline tablets or 7 mefloquine tablets. A prescriber chooses, with the malaria tablets page comparing the four.
Typhoid, rabies and chikungunya
Typhoid is not on Brazil's "most travelers" line. CDC asks travelers to consider it for areas with poor sanitation and unsafe water, rural areas included, for stays of a month or more and for visits to friends or relatives; the shot costs $174 at the median. Hepatitis B, at $149 a dose of the two dose vaccine, is listed for unvaccinated travelers under 60. Rabies is sometimes found in dogs and commonly in some wildlife and bats, and rabies vaccine after a bite is typically available throughout most of the country, so pre-exposure doses ($838 for two) are mainly a topic for cave, forest and animal work. Chikungunya vaccine, $326 at the median, may be considered for stays of six months or more, given CDC's elevated risk wording for Brazil.
What CDC says for Brazil, word for word
Source: CDC, Travelers' Health destination page for Brazil, page last reviewed September 3, 2026, read on October 24, 2026. The text is reproduced without change; it is available free of charge on cdc.gov. Its use here does not imply endorsement by CDC, ATSDR, HHS or the United States Government.
Travel notices: Level 1, Global Measles (May 28, 2025)
| Disease | CDC wording |
|---|---|
| Routine vaccines | Make sure you are up-to-date on all routine vaccines before every trip. Some of these vaccines include • Chickenpox (Varicella) • Diphtheria-Tetanus-Pertussis (DTaP, Tdap, or Td) • Flu (influenza) • Measles-Mumps-Rubella (MMR) • Polio • Shingles |
| COVID-19 | All eligible travelers should be up to date with their COVID-19 vaccines. Please see Your COVID-19 Vaccination for more information. |
| Hepatitis A | Recommended for unvaccinated travelers one year old or older going to Brazil. Infants 6 to 11 months old should also be vaccinated against Hepatitis A. The dose does not count toward the routine 2-dose series. Travelers allergic to a vaccine component should receive a single dose of immune globulin, which provides effective protection for up to 2 months depending on dosage given. Unvaccinated travelers who are over 40 years old, are immunocompromised, or have chronic medical conditions planning to depart to a risk area in less than 2 weeks should get the initial dose of vaccine and at the same appointment receive immune globulin. |
| Hepatitis B | Recommended for unvaccinated travelers younger than 60 years old traveling to Brazil. Unvaccinated travelers 60 years and older may get vaccinated before traveling to Brazil. |
| Typhoid | Consider getting a typhoid vaccine if you might: • Travel to areas with poor sanitation and unsafe water, including rural areas • Spend a long time in Brazil, such as a month or more • Visit friends or relatives Typhoid vaccine is not 100% effective. Practicing safe food and water habits, including washing hands at key times, can also help prevent typhoid fever. |
| Yellow Fever | CDC recommendations: • Vaccine is recommended for travelers ≥9 months old going to the states of Acre, Amapá, Amazonas, Distrito Federal (including the capital city, Brasília), Espírito Santo, Goiás, Maranhão, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Pará, Paraná, Piauí, Rio de Janeiro (including the city of Rio de Janeiro and all coastal islands), Rio Grande do Sul, Rondônia, Roraima, Santa Catarina, São Paulo (including the city of São Paulo and all coastal islands), Tocantins, and designated areas of Bahia; vaccination is also recommended for travelers going to Iguaçu Falls. • Vaccine is not recommended for travel limited to any areas not listed above, including the cities of Fortaleza and Recife. Country entry requirements: Vaccine is not required. Updated April 23, 2025 |
| Malaria | CDC recommends that travelers going to certain areas of Brazil take prescription medicine to prevent malaria. Depending on the medicine you take, you will need to start taking this medicine multiple days before your trip, as well as during and after your trip. Talk to your doctor about which malaria medication you should take. Transmission areas • All areas in the states of Acre, Amapá, Amazonas, Rondônia, and Roraima • Present in the states of Maranhão, Mato Grosso, and Pará, but rare cases in their capital cities (São Luis [capital of Maranhão], Cuiabá [capital of Mato Grosso], Belém [capital of Pará]) • Rare cases and sporadic foci of transmission in rural and forested areas in the states of Espírito Santo, Goiás, Minas Gerais, Mato Grosso do Sul, Piauí, Rio de Janeiro, São Paolo, and Tocantins • No malaria transmission in the cities of Brasília (the capital), Rio de Janeiro, or São Paolo • No malaria transmission at Iguaçu Falls Drug resistance • Chloroquine Species • P. vivax (90%) • P. falciparum (10%) Recommended chemoprophylaxis • Atovaquone-proguanil, doxycycline, mefloquine, tafenoquine • Areas with rare cases: No chemoprophylaxis recommended (insect bite precautions and mosquito avoidance only) Updated April 23, 2025 See footnotes |
| Rabies | Dogs infected with rabies are sometimes found in Brazil. Rabies is also commonly found in some terrestrial wildlife species and bats. If rabies exposures occur while in Brazil, rabies vaccines are typically available throughout most of the country. Rabies pre-exposure vaccination considerations include whether travelers 1) will be performing occupational or recreational activities that increase risk for exposure to potentially rabid animals and 2) might have difficulty getting prompt access to safe post-exposure prophylaxis. Please consult with a healthcare provider to determine whether you should receive pre-exposure vaccination before travel. For more information, see country rabies status assessments. |
| Chikungunya | There is elevated chikungunya risk in Brazil. Chikungunya vaccination may be considered for people traveling or moving to this location if they are planning to stay for an extended period of time (for example, 6 months or more). |
| Measles | Cases of measles are on the rise worldwide. Travelers are at risk of measles if they have not been fully vaccinated at least two weeks prior to departure, or have not had measles in the past, and travel internationally to areas where measles is spreading. All international travelers should be fully vaccinated against measles with the measles-mumps-rubella (MMR) vaccine, including an early dose for infants 6–11 months, according to CDC’s measles vaccination recommendations for international travel. |
| Monkeypox | Monkeypox vaccination is recommended for any adult who anticipates any of the following activities during travel: • Sexual or intimate contact with a new partner • Sexual or intimate contact at a commercial sex venue, like a sex club or bathhouse • Sexual or intimate contact in exchange for money, goods, drugs, or other trade • Sexual or intimate contact in association with a large public event, such as a rave, party, or festival Get your first monkeypox vaccine at least 6 weeks before traveling if you can, or as far as possible before travel if fewer than 6 weeks before you leave. Two doses of vaccine, given 4 weeks apart, are recommended. After completing your first and second vaccine doses it takes about 2 more weeks to get the best protection against monkeypox. Whether or not you've been vaccinated, continue to take steps to reduce your risk of getting monkeypox while you are away. |