Vaccines for Vietnam

The checker above starts on Vietnam: change the departure date, your age or the next country to see how the CDC list, the dose timing and the prices move.

Decides the yellow fever certificate at the first border.

Travel vaccines CDC lists for most or some travelers on this trip

5 vaccines

plus 2 to discuss and routine vaccines up to date

Yellow feverNot needed on this route (Vietnam)
MalariaPrescription tablets for areas of Vietnam
Longest lead time28 days before departure (Hepatitis B, 2 doses (Heplisav-B))
Published price, these vaccines$1,405 median, $1,215 to $1,550

Levels from the CDC destination pages; age 35 used for the Japanese encephalitis schedule. A list to take to a doctor, nurse or pharmacist, not medical advice.

How this is computed
CDC level for each disease on this itinerary, strongest country first. The full CDC wording is on each country page.
DiseaseCDC levelWhereStart at leastMedian price per dose
Hepatitis ACDC: most travelersVietnamAny time before$109
Hepatitis BCDC: most travelersVietnam28 days before$149
MeaslesCDC: most travelersVietnamAsk$115
TyphoidCDC: most travelersVietnam14 days before$174
Japanese encephalitisCDC: some travelersVietnam14 days before$375
ChikungunyaCDC: may be consideredVietnamAny time before$326
RabiesCDC: may be consideredVietnam7 days before$419

Compiled by Radif Partners · Method and sources · CDC page reviewed August 25, 2026, read October 24, 2026

CDC lists three travel vaccines for most travelers to Vietnam: hepatitis A, typhoid and hepatitis B, and for Vietnam the hepatitis B line covers unvaccinated travelers of all ages, with no cutoff at 60. Measles (MMR) and the other routine vaccines come first. Japanese encephalitis is for some travelers, rabies is to be discussed with a clinician, and chikungunya vaccination is generally not recommended. Vietnam has no yellow fever entry requirement at all, so even a trip that starts in Brazil or Kenya needs no certificate at Vietnamese immigration, and CDC does not recommend the vaccine. Malaria is limited to rural areas: none in Hanoi, Ho Chi Minh City, Da Nang, Hai Phong, Nha Trang or Quy Nhon, and no tablets advised in the Mekong and Red River Deltas. At US county health departments the median self-pay price is $109 a dose for hepatitis A, $174 for the typhoid shot and $149 a dose for two dose hepatitis B, or $724 for the three series with visit fees.

Hepatitis B: why Vietnam lists it for every age

On most Asian pages, CDC limits its hepatitis B advice to unvaccinated travelers under 60. The Vietnam page drops that limit: the vaccine is recommended for unvaccinated travelers of all ages. For an older couple on a cruise stop in Ha Long Bay or a retiree spending the winter in Hoi An, that is the line that differs from neighboring Thailand or Cambodia. Past records or a blood test, reviewed with a clinician, show whether the series is needed at all.

Two adult schedules exist. The two dose vaccine is given 28 days apart and costs $149 a dose at the median US price; the three dose vaccine spreads over 180 days and costs $90 a dose. A departure more than 28 days away leaves room for the first schedule, and the last dose of the longer one can be given after the return.

Hepatitis A, typhoid and hepatitis B for Vietnam

Self-pay cost of these travel vaccines

$724

Hepatitis A, 2 doses$217
Typhoid, injection, 1 dose$174
Hepatitis B, 2 doses (Heplisav-B), 2 doses$298
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Food, water and the other two "most travelers" lines

Hepatitis A (for unvaccinated travelers one year old or older) and typhoid complete the main list. Pho stalls in Hanoi's Old Quarter, herbs washed in tap water in the Mekong Delta and ice in iced coffee are where the two diseases come from. One dose of hepatitis A before departure is enough for the trip. The typhoid shot works after 14 days and the oral capsules after 13 days counted from the first capsule, and CDC points out that the vaccine is not 100% effective, so washing hands and choosing cooked food still count.

Where malaria is, and which tablets CDC lists

Vietnam's malaria map is split three ways. In the cities named by CDC (Da Nang, Hai Phong, Hanoi, Ho Chi Minh City, Nha Trang and Quy Nhon) there is none. In the Mekong and Red River Deltas, cases are rare and CDC advises only insect bite precautions. In other rural areas, tablets are advised, but the list depends on the province. Ten provinces, mostly in the Central Highlands and the south (Binh Duong, Binh Phuoc, Dak Lak, Dak Nong, Gia Lai, Khanh Hoa, Kon Tum, Lam Dong, Ninh Thuan and Tay Ninh), take atovaquone-proguanil, doxycycline or tafenoquine, without mefloquine. Elsewhere in rural Vietnam, mefloquine is on the list too. CDC reports resistance to chloroquine and mefloquine.

A motorbike loop through the Central Highlands around Buon Ma Thuot or Da Lat crosses that first group of provinces. For a week there, atovaquone-proguanil means 16 tablets (about $23 at the price pharmacies pay) and doxycycline 37 tablets; in other rural areas, weekly mefloquine means 7 tablets, about $26. Which one fits is a prescriber's decision.

Malaria tablets for rural Vietnam

Atovaquone-proguanil for 7 days in Vietnam

16 tablets

CDC for this countryPrescription medicine for the areas listed
Drugs CDC lists hereAtovaquone-proguanil, Doxycycline, Mefloquine, Tafenoquine
Start and stopdaily, from 2 days before to 7 days after the risk area
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Japanese encephalitis in the countryside

Rice paddies cover the deltas and the terraces of Sapa, which is the rural setting CDC's advice on Japanese encephalitis is about. CDC lists the vaccine for some travelers to Vietnam: people moving there, staying a month or more in affected areas or traveling there often. For shorter stays, CDC says to consider it with rural visits, hiking, camping, nights without air conditioning, screens or bed nets, or an unclear itinerary, and not for short trips to urban areas. Adults aged 18 to 65 take the two doses 7 days apart, which means starting 14 days before departure; other ages wait 28 days between doses and start 35 days ahead. Each dose costs $375 at the median.

Is there still time for Japanese encephalitis?

Japanese encephalitis: when to start

14 days before

Doses2 doses: day 0, day 7
Protection7 days after the last dose
Published price per dose$375 median, $325 to $420 (9 departments)
Series, median total with fees$820 ($650 to $880)
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No yellow fever certificate, from any route

CDC's entry line for Vietnam reads that the vaccine is not required, with no exception for travelers coming from risk countries. A trip that combines a safari in Tanzania or the Amazon with Vietnam therefore asks nothing at Vietnam's border. The certificate question returns only if the next country on the route has its own rule: Thailand, Cambodia and the Philippines ask one from travelers arriving from risk countries, so the order of the stops matters more than Vietnam itself. The certificate page sorts the countries by rule.

Rabies and chikungunya

CDC notes that dogs infected with rabies are sometimes found in Vietnam and that rabies vaccines are typically available throughout most of the country if a bite happens. Pre-exposure doses are a "consider" line, weighed with a clinician for cyclists, cavers, long stays and work with animals; two doses cost $838 at the median. Chikungunya vaccination is generally not recommended for Vietnam, and bite prevention is CDC's main advice, which also covers dengue, the subject of a global CDC notice.

What CDC says for Vietnam, word for word

Source: CDC, Travelers' Health destination page for Vietnam, page last reviewed August 25, 2026, read on October 24, 2026. The text is reproduced without change; it is available free of charge on cdc.gov. Its use here does not imply endorsement by CDC, ATSDR, HHS or the United States Government.

Travel notices: Level 1, Global Dengue (September 3, 2026) · Level 1, Global Measles (May 28, 2025)

DiseaseCDC wording
Routine vaccinesMake sure you are up-to-date on all routine vaccines before every trip. Some of these vaccines include
• Chickenpox (Varicella)
• Diphtheria-Tetanus-Pertussis (DTaP, Tdap, or Td)
• Flu (influenza)
• Measles-Mumps-Rubella (MMR)
• Polio
• Shingles
COVID-19All eligible travelers should be up to date with their COVID-19 vaccines. Please see Your COVID-19 Vaccination for more information.
Hepatitis ARecommended for unvaccinated travelers one year old or older going to Vietnam.
Infants 6 to 11 months old should also be vaccinated against Hepatitis A. The dose does not count toward the routine 2-dose series.
Travelers allergic to a vaccine component should receive a single dose of immune globulin, which provides effective protection for up to 2 months depending on dosage given.
Unvaccinated travelers who are over 40 years old, are immunocompromised, or have chronic medical conditions planning to depart to a risk area in less than 2 weeks should get the initial dose of vaccine and at the same appointment receive immune globulin.
Hepatitis BRecommended for unvaccinated travelers of all ages traveling to Vietnam.
TyphoidRecommended for most travelers.
Typhoid vaccine is not 100% effective. Practicing safe food and water habits, including washing hands at key times, can also help prevent typhoid fever.
Yellow FeverCDC recommendations: Vaccine is not recommended.
Country entry requirements: Vaccine is not required.
Updated April 23, 2025
MalariaCDC recommends that travelers going to certain areas of Vietnam take prescription medicine to prevent malaria. Depending on the medicine you take, you will need to start taking this medicine multiple days before your trip, as well as during and after your trip. Talk to your doctor about which malaria medication you should take.
Transmission areas
• Rural areas only; rare cases in the Mekong and Red River Deltas
• None in the cities of Da Nang, Hai Phong, Hanoi, Ho Chi Minh City (Saigon), Nha Trang, and Quy Nhon
Drug resistance
• Chloroquine and mefloquine
Species
• P. vivax (55%)
• P. falciparum (44%)
• P. knowlesi, P. malariae, and P. ovale (rare)
Recommended chemoprophylaxis
• Provinces of Bình Dương, Bình Phước, Đắk Lắk, Đắk Nông, Gia Lai, Khánh Hòa, Kon Tum, Lâm Đồng, Ninh Thuận, Tây Ninh: Atovaquone-proguanil, doxycycline, tafenoquine
• All other areas with malaria transmission (except Mekong and Red River Deltas): Atovaquone-proguanil, doxycycline, mefloquine, tafenoquine
• Mekong and Red River Deltas: No chemoprophylaxis recommended (insect bite precautions and mosquito avoidance only)
Updated April 23, 2025
See footnotes
Japanese EncephalitisRecommended for travelers who
• Are moving to an area with Japanese encephalitis to live
• Spend long periods of time, such as a month or more, in areas with Japanese encephalitis
• Frequently travel to areas with Japanese encephalitis
Consider vaccination for travelers
• Spending less than a month in areas with Japanese encephalitis but will be doing activities that increase risk of infection, such as visiting rural areas, hiking or camping, or staying in places without air conditioning, screens, or bed nets
• Going to areas with Japanese encephalitis who are uncertain of their activities or how long they will be there
Not recommended for travelers planning short-term travel to urban areas or travel to areas with no clear Japanese encephalitis season.
RabiesDogs infected with rabies are sometimes found in Vietnam.
If rabies exposures occur while in Vietnam, rabies vaccines are typically available throughout most of the country.
Rabies pre-exposure vaccination considerations include whether travelers 1) will be performing occupational or recreational activities that increase risk for exposure to potentially rabid animals and 2) might have difficulty getting prompt access to safe post-exposure prophylaxis.
Please consult with a healthcare provider to determine whether you should receive pre-exposure vaccination before travel.
For more information, see country rabies status assessments.
ChikungunyaAll travelers should take steps to prevent mosquito bites. Chikungunya vaccination is generally not recommended. Travelers who wish to consider vaccination can visit “What to consider before traveling” on the chikungunya vaccines page to learn more.
MeaslesCases of measles are on the rise worldwide. Travelers are at risk of measles if they have not been fully vaccinated at least two weeks prior to departure, or have not had measles in the past, and travel internationally to areas where measles is spreading.
All international travelers should be fully vaccinated against measles with the measles-mumps-rubella (MMR) vaccine, including an early dose for infants 6–11 months, according to CDC’s measles vaccination recommendations for international travel.
MonkeypoxMonkeypox vaccination is recommended for any adult who anticipates any of the following activities during travel:
• Sexual or intimate contact with a new partner
• Sexual or intimate contact at a commercial sex venue, like a sex club or bathhouse
• Sexual or intimate contact in exchange for money, goods, drugs, or other trade
• Sexual or intimate contact in association with a large public event, such as a rave, party, or festival
Get your first monkeypox vaccine at least 6 weeks before traveling if you can, or as far as possible before travel if fewer than 6 weeks before you leave. Two doses of vaccine, given 4 weeks apart, are recommended. After completing your first and second vaccine doses it takes about 2 more weeks to get the best protection against monkeypox. Whether or not you've been vaccinated, continue to take steps to reduce your risk of getting monkeypox while you are away.

Questions travelers ask

Why does CDC list hepatitis B for older travelers to Vietnam?

The Vietnam page recommends hepatitis B for unvaccinated travelers of all ages, without the under 60 limit used on several other Asian pages such as Thailand or Cambodia. Older travelers without a record of vaccination fall into that group. A clinician can check past vaccination or immunity and choose between the two dose and three dose adult schedules, depending on the time left before departure.

Are malaria pills needed for Hanoi or Ho Chi Minh City in Vietnam?

CDC reports no malaria in Hanoi, Ho Chi Minh City, Da Nang, Hai Phong, Nha Trang or Quy Nhon, and only rare cases in the Red River and Mekong Deltas, where it advises bite precautions without tablets. Tablets are advised for other rural areas, with a narrower drug list in ten provinces of the Central Highlands and south. A prescriber reviews the exact route.

Does Vietnam ask for a yellow fever certificate after South America?

No. According to CDC, Vietnam has no yellow fever vaccination requirement for entry, including for travelers arriving from countries with yellow fever risk. CDC does not recommend the vaccine for Vietnam either. A certificate can still be asked at the next border if the trip continues to a country that applies a rule to arrivals from risk countries, such as Thailand or Cambodia.

Next steps

CDC pages, price lists and data behind this page

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Independent publisher of travel vaccine checklists and cost estimates built from CDC destination advice and the fee schedules of US public health departments

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CDC advice is quoted from the destination page of each country; prices are the self-pay lists of US public health departments, dated, not quotes. Your clinician decides what you need from your health, age, plans and past vaccines.

Data of 2026, CDC pages and price lists last read on